Gordon Lam and Esther Kwan in A Recipe for the Heart - He left her for another woman.
Louis Koo and Miriam Yeung in A Recipe for the Heart - She cheated on him with Carlo Ng, and they broke up because she blamed him for her infidelity.
Bobby Au Yeung and Monica Chan in A Recipe for the Heart - He focused too much on Cooking and his preperation for his Competition against Paul Chun, and neglected her.
Lawrence Ng and Joyce Tang in A Taste of Love - They broke up because he thought she went back to her ex-boyfriend. Later in the series they got back together, but broke up again, because he loved Flora Chan.
Lawrence Ng and Nancy Wu in At Home with Love - They broke up for the Second Time, because they both loved someone else.
Timmy Hung and Shirley Yeung in Angels of Mission - Timmy broke up with Shirley because he didn't like the way she treated him.
Jessica and Bosco - Life made simple - because bosco thought that jessica wasnt worth it in the end and he was feeling the pressure from his family and from leila.
Leila and Bosco - Life made simple - because she didnt want to be with him any more..think it was because his business failed..she then went with kenneth..?
Bowie Lam and Chan Chai Ping - healing hands 3 - breaks up with her because he felt she was suffocating him..he ended up in hospital..
Gallen Lo and Kenix Kwok in At the Threshold of An Era - He broke up with her because he thinks that she will eventually get hurt by him if they remain together.
Gallen Lo and Flora Chan in At the Threshold of An Era - He still loved Kenix Kwok, and she hated him for his lack of committment.
Sunny Chan and Maggie Siu in At the Threshold of An Era - She hated him for being friends with Gallen Lo, and he misunderstood that she was with Nicky Wu.
- Raymond Cho & Maria Chan in Welcome to the House : Raymond doesn't like Maria anymore & his family knew that Maria was a destroyer in their house.
- Chris Lai & Shermon Tang in Welcome to the House : He cheated on her.
- Charmaine Sheh & her first boyfriend in The White Flame : He was dated with another girl because Charmaine didn't want to follow him to study abroad.
- Edmond So & June Chan in Family Man : She had mental problem & he still liked Jay Lau.
- Griselda Yeung & Johnson Lee in Welcome to the Hosue : Because she will get marry soon & she didn't like Johnson anymore.
- Melissa Ng & Tse Kwan Ho in Dream of Colours : Because she was jealous his relationship with Myolie Wu (I think?? or maybe Tse Kwan Ho started to like Myolie?)
Moses Chan and Tracy Ip in Heart of Greed - They broke up because he was in love with Linda Chung.
Vinci Wong and Natalie Tong in Life Art - They broke up because he felt that she was only using him.
Roger Kwok and Florence Kwok in At the Threshold of An Era - They decided to have a separation period after his parents' deaths, and didn't get back together.
Roger Kwok and Fiona Yuen in A Smiling Ghost Story - She thought he was cheating on her with Maggie Cheung.
Joe Ma and Monica Chan in A Smiling Ghost Story - They broke up because he wanted her to sleep with one of his customers.
Lawrence Ng and Yoyo Mung in At Home with Love - They broke up because, he felt that it wouldn't work out after she decided to work for Sublime (Raymond Cho's Company).
Stephen Au and Maggie Cheung in Ups and Downs In the Sea of Love - She found out that he was trying to steal her money, and the one she truly loved was Nick Cheung anyway.
Evergreen Mak and Yoyo Mung in Forensic Heroes - She didn't like the was he was (His Personality).
Moses Chan and Halina Tam in Healing Hands 3 - Their personalities clashed, and they had too many arguements.
Bobby Au Yeung and Jessica Hsuan in Dicey Business - She slept with Michael Miu.
Wong Hei and Jessica Hsuan in A Matter of Customs - He treated her bad after he went undercover.
Jack Wu and Myolie Wu in Net Deception - She thought that he never loved her, and only came close to her to find evidence to prosecute her brother, Wong Hei.
Michael miu and florence kwok (or you can say stephen huynh+karen lee) - dicey business - didnt say..think they just fell out and ended it.
Jessica and Cheng zhi sing - Golden Faith - because he was gay?
Mark Kwok and Yvonne Ho - Under the canopy of love -because she kept thinkig about getting a rich boyfriend, and didnt want to marry him, but they got back together.
- Gilbert Lam & Mark Kwok in To Catch the Uncatchable : Gilbert can't accept that he liked a guy.
- Ben Yeo & "Jane" in Food for Life : In Singapore - Ben's mother didn't allow them to be together, In HK - Jane cheated on him.
- The young couple (the girl who worked in 7/11 & her boyfriend) in On the First Beat : The girl said the guy didn't understand her. (they only appeared in the first eps.)